Markedly Increased High-Mobility Group Box 1 Protein in a Patient with Small-for-Size Syndrome
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چکیده
منابع مشابه
Markedly Increased High-Mobility Group Box 1 Protein in a Patient with Small-for-Size Syndrome
Background. Small-for-size syndrome (SFSS) occurs in the presence of insufficient liver mass to maintain normal function after liver transplantation. Murine mortality following 85% hepatectomy can be reduced by the use of soluble receptor for advanced glycation end products (sRAGE) to scavenge damage-associated molecular patterns and prevent their engagement with membrane-bound RAGE. Aims. To e...
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High-mobility group box 1 protein (HMGB1), a member of highly conserved non-histone DNA binding protein family, has been studied as transcription factor and growth factor. Secreted extracellularly by activated monocytes and macrophages or passively released by necrotic or damaged cells, extracellular HMGB1 is a potent mediator of inflammation. Extracellular HMGB1 has apparently contrasting biol...
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Background: Stroke is a leading cause of death all around the world, and ischemic stroke is considered to be the most common stroke type. Toll-like receptors (TLRs) are important molecules for detection of both pathogen invasion and tissue damage. In this regard, the purpose of this study was to assess the expression level of TLR2 on monocytes in patients with ischemic stroke and to evaluate th...
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ژورنال
عنوان ژورنال: Case Reports in Transplantation
سال: 2014
ISSN: 2090-6943,2090-6951
DOI: 10.1155/2014/272498